A particular file is crashing Polybuilder, both in the 32bit MapInfo 15.0 version, and the reintroduced back in Discover 2017 64bit,
Solution
This was due to a low level .MAP file format (where MapInfo stores vectors), and is resolved in Discover 2017 Update or later.
To workaround in previous version you need to open a Mapbasic window and enter this command, then press Return to execute it -
Commit table Geology as "C:\Geology_new.tab" Blocksize 512
Where Geology is the layer name of your existing file, and a new tab file to save it to.
Open the new tab file and it should work fine in Polybuilder.